When it comes to European Football, and especially for the UEFA Champions League - the home pitch definitely plays a great advantage. The home supporters chanting their songs, waving their flags, and creating that atmosphere that sends the chills against the visiting team is just as crucial as the 11 players of the home team who are taking to the pitch.

But then, of course, eventually it is up to the 11 men on the pitch to make use of the home support to their advantage, and hopefully bring a victory. 16 teams remain in the UEFA Champions League, and two legs are set to be played in the knockout round of 16. IN the meantime, let's see what's in store for the first leg, and the predictions on who are favored to win the first leg.

Predictions on First Leg of Knockout Round of 16 in UEFA Champions League:

Schalke 04 vs. FC Porto. Bet on FC Porto to score an upset at the Schalke 04 home pitch.

AS Roma vs. Real Madrid. Bet on AS Roma to hold their ground at the AS Roma home pitch. Besides, Real Madrid haven't been in form, losing their last two La Liga matches.

Olympiakos vs. Chelsea. Bet on Olympiakos to win at home. Chelsea are a good team, but it's very difficult to win at the Olympiakos home pitch.

Liverpool vs. Inter Milan. Bet on Inter Milan to upset Liverpool at Anfield. Liverpool haven't been too great, even losing in the FA Cup to lowly Barnsley.

Celtic vs. Barcelona. Bet on Celtic to hold their ground at the Celtic home pitch. Barcelona might be great, but their Fantastic Four of Thierry Henry, Lionel Messi, Samuel Eto'o and Ronaldinho have not been "fantastic" lately.

Lyon vs. Manchester United. Bet on Lyon to uphold their ground in French soil. Manchester United might be on a streak, but Manchester United have a difficult time winning in France.

Fenerbahce vs. FC Sevilla. Bet on Fenerbahce to hold their ground at their home pitch against Sevilla.

Arsenal vs. AC Milan. Bet on AC Milan to upset Arsenal at the Emirates Stadium. Arsenal were recently thrashed by Manchester United in the FA Cup, and it seems that they're lacking some gusto with the absence of key players.

Bet on the UEFA Champions League, and visit the UEFA Champions League sportsbook. Half-time/Full-time results can also be bet as well as against the spread or money line bets. You can even bet on a draw.

Italian Serie A club AC Milan will face Ukrainian Premier League club Shaktar Donetsk in another UEFA Champions League group stage match. Shaktar and AC Milan faced each other last October 27 at the San Siro in Milan, Italy, and AC Milan were able to beat Shaktar 4-1. Alberto Gilardino and Clarence Seedorf scored 2 goals each for AC Milan in that 4-1 win over Shaktar Donetsk.

Shkatar Donetsk and AC Milan both lead the UEFA Champions League Group D with 6 points each. Certainly, the winner of the Shaktar-AC Milan match will be the solo leader of Group D.

Shaktar Donetsk will host AC Milan at the RSC Olympiyskiy Stadium in Donetsk, Ukraine for the upcoming November 7 Champions League match. Shaktar Donetsk coach Mircea Lucescu will be relying on the likes of Cristiano Lucarelli, Dmytro Chygrnskiy and Ilsinho to provide the home win.

AC Milan coach Carlo Ancelotti will be sure to have Kaka, Clarence Seedorf, Andrea Pirlo and Alessandro Nesta on the roster if they hope to win again against Shaktar. Even Brazilian star forward and former Real Madrid striker Ronaldo might be clear to see action after missing several matches for AC Milan due to recovery from injuries.

Oddsmakers are considering AC Milan as the favorite to win considering AC Milan's last performance against Shaktar.

To check the latest UEFA Champions League betting tips and odds, or to bet on AC Milan vs. Shaktar Donetsk, click here.